Molecular Cell Biology ACRIS® Antibodies   More than 18,500 antibodies against proteins in Apotosis, Cancer research, Cell Surface Antigen, Cell Cycle, Lipid Metabolism, Neurobiology, Signal Transduction and many more. Also available are a comprehensive range of secondary antibodies for Western, IHC etc. Just use our Ab Search! to locate the antibodies of your interest.[AB Search! Form]     BioLegend® Reagents for Immunology and Cell Biology Research   The genomic era has given way to realization that elucidating protein levels, distribution, interactions, and modification are key to understanding cell function and disease. BioLegend develops high quality and affordable antibody based research products covering the areas of cell immunophenotyping, cytokine, chemokines, adhesion, cancer research, cell-cycle analysis, and apotosis.[More Info]     BioLegend® ELISA Max™ Set and ELISA Antibodies Pairs   ELISA Max™ Set Standard and ELISA Max™ Set Deluxe are specifically engineered for accurate recovery and measurement of analytes in complex fluids, such as serum and plasma (as well as activated cell cultures) without any interference by confounding serum factors, such as heterophilic antibody or rheumatoid factor. ELISA Max™ Set Standard includes pre-titrated capture antibody, pre-titrated biotinylated detection antibody, pre-titrated Avidin-HRP, conveniently-sized assay calibration standards, and easy-to-follow instructions. [More Info]     Epigentek EpiQuik™ Chromatin Immunoprecipitation (ChIP) kit   EpiQuik™ Chromatin Immunoprecipitation (ChIP) Kit allows the researchers to perform chromatin immunoprecipitation (ChIP) at extraordinarily rapid speeds and consistency. The EpiQuik ChIP kits are suitable for combining the specificity of immunoprecipitation with qualitative and quantitative PCR, MS-PCR, DNA sequencing, and southern blot as well as DNA microarray. Optimised EpiQuik ChIP kits for Methyl-Histone ( H3-K4 / H3-K9 / H3-K27), Methylated DNA, Methylated CpG Binding Domain Protein 2 and Acetylated Histone (H3 /H4) are available. [More Info]     Epigentek Methylamp™ DNA Modification Kit   Methylamp™ DNA Modification Kit is developed using Epigentek's uniquely simplified and streamlined bisulfite method that completely converts unmethlyated cytosine to uracil (>99.8%) with lowest level of DNA degradation. The entire procedure can be completed in less than 2 hrs. The Methylamp DNA Modification Kit is suitable for MS-PCR, real time MS-PCR, methylation sequencing, and pyrosequencing, as well as methylation microarray. [More Info]     Epigentek EpiQuik™ Methyltransferase Activity/Inhibition Kits   EpiQuik™ Methyltransferase Activity/Inhibition Kits enable researchers to measure methyltransferase activity or inhibition in less than 3 hours using colormetric-based assay. EpiQuik Methyltransferase Activity/Inhibition Kits optimised for Dnmt, Histone H3-K4, H3-K9 and H3-K27 are currently available. The kits are suitable for measuring methyltransferase activity/inhibition from a broad range of species including mammalian cells/tissues, plants, and bacteria. [More Info]     EVROGEN Trimmer ™ cDNA Normalization Kit   Evrogen TRIMMER kit is based on the propietary DSN (Duplex Specific Nuclease) Technology that involves denaturation-reassociation of cDNA, degradation of ds-fraction formed by abundant transcripts and PCR amplification of the equalized ss-DNA fraction. TRIMMER is specially developed to normalize cDNA enriched with full-length sequences and does not require physical separation of single stranded DNA and double stranded DNA. TRIMMER allows user to obtain normalized cDNA samples with the size of individual cDNAs range from 0.5 to 4.5 kbs. [More Info]     EVROGEN PS-CFP 2: Dual Colour Photo-switchable Fluorescent Protein   PS-CFP2 is a monomeric photoactivatable dual-color protein capable of irreversible photoconversion from cyan to green fluorescent form in response to 405 nm light irradiation. After complete photoconversion more than 2000-fold growth in the green-to-cyan fluorescence ratio is observed, making PS-CFP2 the most contrasting monomeric photoactivatable fluorescent protein. PS-CFP2 has high pH stability before photoactivation. PS-CFP@ is suitable for protein labeling, protein movement tracking and FRET applications. [More Info]     EVROGEN J-Red™ :A Novel Non-Aggregating Red Fluorescent Protein#   J-Red is a novel red fluorescent protein (emission max 610nm) obtained by mutagenesis of Anthomedusae jellyfish chromoprotein. J-Red is non-aggregating as demostrated in successful fusion constructs and gel electrophoresis data. These unique properties make J-Red an excellent reporter for labelling autofluorescence biomaterial, such as blood, plant tissue or marine organisms, or as fusion protein for protein localization studies.[More Info]     EVROGEN Kindling Red™ In Vivo Tracking Vectors#   Kindling-Red™ in vivo tracking vectors are novel tool for direct and precise fluorescent photolabeling and tracking of individual cell, cell organelle and protein in vivo. Kindling-Red™ in vivo tracking vectors encode an unique red kindling fluorescent protein KFP-Red (as featured in Nature Biotechnology), that can be reversibily photoactivated/quenched by brief exposure of low power green laser and blue laser light respectively. Irreversible conversion from nonfluorescent to a stable bright-red fluorescent (kindling) can be achieved by exposure to intense or enduring green irradiation. [More Info]     EVROGEN Novel Fluorescent Protein Expression Vectors#   Superbright and non-oligomeric novel fluorscent proteins from EVROGEN are convenient and efficient tools for monitoring gene expression, protein localization & interaction, cellular dynamics and drug screening. The Cop-Green™(green), Phi-Yellow™(yellow) and HcRed-Tandem™(far-red) Flourescent Proteins have distinct excitation and emission spectra suitable for the commonly available filters and are ideal for multicolor labeling and FRET applications. [More Info]     ICL Antibodies vs Affinity Tags and Fusion Proteins   Immunology Consultants Laboratory, Inc. (ICL) offers wide range of high quality affinity purified antibodies against affinity tags and fusion proteins commonly used in molecular and cell biology applications. The antibodies are suitable for western blot, ELISA, immunoprecipitation.[More Info]     IMGENEX Antibodies   IMGENEX offers a large selection of antibody reagents to factors involved in major cellular process such as DNA Fragmentation; DNA Damage & Repair; Chromatin; Telomere Associated Factors; Cleaved Antigen; Apotosis; TNF Family & Death Receptors; Toll-Like Receptors; NFkB Pathway; Development & Differentiation; Neurobiology; Transcription Factors etc.[More Info]     IMGENEX Provectin™ Protein Delivery System   The ProVectin™ Protein Delivery Reagent is remarkably effective for delivering a number of different macromolecules such as fluorescently labeled antibodies, high and low molecular weight dextrans, phycoerythrin-BSA (300,000 Mol.Wt.), caspase 3, caspase 8, granzyme B, and b-galactosidase into the cytoplasm of a variety of different adherent and suspension cells. The efficiency varies from 20-100% of the cells transduced and up to 50% of the input protein gets incorporated into the cells.[More Info]     IMGENEX RetroMax™Expression System   RetroMax™ Retrovirus Vector System is based on the pCL vector system and has been designed to maximize recombinant retrovirus titers in a simple, efficient, and flexible experimental system. All members of the RetroMax expression vector family (pCLXSN, pCLNCX, pCLNRX, and pCLNDX) have an extended packaging signal and are derived from safety modified retrovirus vectors in which the gag open reading frame has been stopped by a point mutation.[More Info]     IMGENEX INSTA Blot™ Ready made Western Blots   IMGENEX INSTA Blot Ready Made Western Blot Membranes provide an instant solution for screening the expression of a particular protein in 12 major organ/tissues from human (cat # IMB103), mouse (IMB101) or rat (IMB102);and from cell lines with various treatments (IMB105). In addition to the INSTA-Blot, IMGENEX also offers individual tissue and cell lysates from different species and drug treatments for researchers who want to create their own western blots.[More Info]     Ingenio™ : The Next Generation of Electroporation   Mirusbio ’s Ingenio™ is a broad spectrum solution that supports high efficiency electroporation with minimal toxicity. It replaces standard electroporation solutions including phosphate buffered saline and serum-free media. Ingenio is compatible with multiple instruments and facilitates a wide range of applications requiring nucleic acid delivery to cells. [More Info]     MIRUS TransIT®-TKO siRNA Transfection Reagent   The gold standard for siRNA delivery, Trans IT-TKO® Transfection reagent enables highly efficient siRNA transfection with significant reduced level of cell damage as compared to cationic-liposome based transfection reagents. Also available are Trans IT-TKO® HTP-96 well plate for siRNA screening project. Cell type sucessfully tested includes A549, BNL.CL2, C2C12, C6, CHO-KI, COS-7, Daoy, DB-TRG-05MG, D1-TNC1, DU145, HEK 293, HeLa, Hepa 1-6, Hepa1cLc7, Hep G2, human astrocytes, Jurkat, Keratinocytes (NIKS), MCF-7, Neuro-2a, NIH 3T3, PC-3, primary mouse hepatocytes, primary rat hepatocytes, RAW 264.7, SK-N-MC, THP-1, Vero. [More Info]     MIRUS TransIT®-siQUEST siRNA Transfection Reagent   TransIT®-siQUEST™ Transfection Reagent enables highly efficient siRNA transfection with significantly reduced levels of cell damage as compared to cationic-liposome based transfection reagents. Transfections are most effective when carried out in complete growth media, with no media change or serum addition required. The unique lipopolyplex formulation offers advantages in select cell types. Now you can choose from two state-of-the-art siRNA transfection reagents: the tried and tested Trans-IT-TKO® Reagent or the new TransIT®-siQUEST™ Reagent.[More Info]     MIRUS TransIT® LT-1 and LT-2 Broad based Transfection Reagents   TransIT®-LT1 and LT-2 Transfection Reagent are designed to achieve high transient and stable transfection efficiencies in a variety of cell types, with minimal cellular toxicity. Highest transfection efficiencies are achieved when transfections are performed in the presence of serum-containing media, with no media change. This robust reagent is supplied with an optimized protocol and a ready-to-use single vial, which allows for high reproducibility. More than 60 cell types have been sucessfully tested to date [More Info]     MIRUS TransIT® Cell Line Specific Transfection Reagents   TransIT® cell line specific transfection reagents are developed from MIRUS Corporation’s extensive protein, polymer and lipid libraries to generate specialized formulations that provide unsurpassed transfection efficiency while maintaining minimal cellular toxicity. TransIT® formluation optimized for Keratinocyte; 3T3; 293; COS; CHO; HeLa and Insect cell respectively are currenty available.[More Info]     MIRUS TransIT®-Neural Transfection Reagent   The TransIT® Neural Transfection Reagent is a novel formulation specifically developed to achieve superior transfection efficiency in a wide range of neural cell types without sacrificing cell viability. This ready-to-use reagent results in up to 75% efficiency using pGFP as the reporter plasmid. Highest efficiencies are achieved when transfections are performed in the presence of serum-containing media, with no media change.Neural cell type sucessfully tested include C6, Daoy, DBTRG-05MG, DI-TNC1, HCN-1A, Neuro-2a, PC-12, Secondary human astrocytes, SK-N-MC, SVG p12 . [More Info]     MIRUS TransIT® - Prostate Transfection Kit   This novel kit is specifically optimized to provide superior transfection efficiency in prostate cells without sacrificing cellular health. The kit provides all the attributes of the trusted TransIT® Reagent line developed by MIRUS Corp.: high efficiency, low toxicity, simplicity of use, and reproducibility. Transfections with the TransIT® Reagents do not require media changes and can be carried out in serum-containing media. In addition, the TransIT® - Prostate Transfection Kit is quality control tested on ATCC DU-145 cells. [More Info]     MIRUS TransIT®-Jurkat Transfection Reagent   The TransIT® - Jurkat Transfection Reagent, developed by Mirus Corporation, is a novel reagent specifically optimized to provide superior transfection efficiency in Jurkat cells. Jurkat cells (human T-lymphocyte; acute T-cell leukemia) have been inherently difficult to transfect, yet have remained a prevalent cell line in the immunological research field. [More Info]     MIRUS TransIT®- in vivo Delivery System   TransIT®-in vivo Delivery System is the first set of reagent designed specifically for introducing nucleic acid into live mice and rats allowing for organ specific genetic studies. With Trans IT in vivo Gene Delivery System, high efficiency delivey of exogenous DNA complexes into tissue can be achieved without the use of virus.[More Info]     MIRUS LabelIT® - Microarray Labeling Kits   Label IT® µArray Labeling Kits offer a convenient chemical labeling method optimized for microarray application. Mirus' Label IT® technology is designed to covalently attach biotin or marker molecules to guanine residues of DNA in one simple chemical reaction. Label IT® technology elimates labeling bias resulted from modified nucleotides and enzymatic replication. The versatile Label IT® µArray™ Kits allow any type of nucleic acid sample - mRNA, cDNA, or cRNA - to be directly and uniformly labeled with biotin or other marker molecule.[More Info]     MIRUS™ siXpress PCR Vector System   Mirus siXpress PCR Vector Systems allow you to generate a variety of siRNA expression cassettes by PCR and transfect them into cells to determine the siRNA sequence that achieves the highest knockdown of gene expression. The kits include a promoter specific plasmid of your choice: human U6, human H1 or mouse U6, the necessary promoter primers, a control luciferase siRNA vector and primer and Mirus' most popular broad spectrum transfection reagent TransIT®-LT1 Reagents for efficient delivery of the PCR cassettes into mammalian cells.[More Info]     SA Biosciences RT2 Profiler™ PCR Array   RT2 Profiler™ PCR Array combines the profiling capabilities of microarrays with the performance of Real-Time PCR. Each RT2 Profiler PCR Array is a 96-well plate predispensed with gene specific primer sets for 84 thoroughly researched and relevant, pathway focused genes. These primers sets are optimized for SYBR Green detection using RT2 real time PCR Master Mixes. More than 100 pathway focus PCR arrays are currently available [More Info]     SA Biosciences RT2 Genome-wide qPCR Primer Assay   RT² qPCR Primer Assay is the most reliable SYBR® Green-based quantitative real-time PCR assay for gene expression analysis. Our experimentally verified design algorithm yields gene-specific qPCR assays characterized by uniform and high PCR efficiencies and standardized amplification conditions. Every RT² qPCR Primer Assay is subjected to rigorous experimental verification. [Find your primer set here!]     SA Biosciences RT2 miRNA PCR Array   RT² miRNA PCR Array accurately analyzes the expression of multiple micro RNA sequences at the same time on ANY real-time PCR instrument. Each 96- or 384-well plate contains SYBR Green optimized and experimentally validated assays for either the entire human or mouse miRNA genome or pathway-focused sets of human or mouse miRNA sequences. SA Biosciences' proprietary miRNA detection technologies enable uniformly high PCR amplification efficiencies, allowing simultaneous detection of miRNA under uniform cycling conditions. These technologies also provide the RT² miRNA PCR Array with high sensitivity, specificity and accuracy. [More Info]     SA Biosciences Genome-wide RT2 miRNA qPCR Assay   RT² miRNA qPCR Assays are the most reliable and accurate SYBR Green-based quantitative real-time PCR assay for analyzing the expression of any human miRNA sequence. Our experimentally verified primer design algorithm distinguishes miRNA family members with single nucleotide mismatches. The resulting miRNA-specific qPCR assays are experimentally certified for their specificity and uniformly high amplification efficiencies under standardized cycling conditions. [More Info]     SA Biosciences SureSilencing ™ siRNA Array   SureSilencing siRNA Array is the latest technological innovation for conducting functional studies on your pathway of interest through RNA interference (RNAi). Validated siRNA (2 sequences per gene) for 42 key pathway-focused genes with appropriate RNAi controls are arrayed on a 96-well plate. Following a simple reverse transfection protocol with the siRNA, you can directly determine the phenotype of the cells on the same plate with colorimetric, luminescent or fluorescent cell-based assays.[More Info]     SA Biosciences SureSilencing ™ shRNA Plasmid   SureSilencing shRNA Plasmids specifically knock down the expression of every human, mouse or rat gene by RNA interference under transient or stable transfection conditions. The availability of at least two effective shRNA designs, guaranteed to knock down expression of the targeted gene, allow you to control for non-specific and off-target effects. Use the SureSilencing shRNA Plasmids to examine the function of individual genes in detail. [More Info]     SA Biosciences SureSilencing ™ SilenciX Knockout Cell Lines   SureSilencing SilenciX Knockout cell lines provide ready-to-use in vitro cellular models for specific silencing of human target genes. The SilenciX technology is based on a replicative plasmid leading to the production of a few episomal copies per cell and no random integration. The low level of siRNA expression and the access to a very efficient algorithm for shRNA design, coupled to a genome-wide blast screening prohibit any unwanted off-target effects. [More Info]     SA Biosciences Methyl-Profiler ™ DNA Methylation PCR System   Methyl-Profiler DNA Methylation PCR System is an innovative technology enabling fast and accurate detection of CpG island DNA methylation profiles of individual genes as well as disease or pathway focused gene panels. This technology replaces the tedious and low-throughput bisulfite-based methods with a simple restriction digest and quantitative PCR. [More Info]     SA Biosciences ChampionChIP ™ qPCR System   ChampionChIP™ System provides the only complete platform for investigating the in vivo interactions between protein and DNA that are central to epigenetics and regulating gene expression. The system offers a robust one-day ChIP kit and genome-wide qPCR primers for analyzing genomic DNA associated with transcription factors and co-regulators, modified and unmodified histones, chromatin remodelling factors and other nuclear proteins. [More Info]     SA Biosciences Cignal ™ Reporter Assay System   Cignal Reporter Assay System provides a comprehensive solution for monitoring diverse cell signaling pathways. The Cignal family of pathway reporters are valuable tools for assessing the biological impact of RNA interference, protein overexpression or small molecule drug treatment. Cignal Reporters enable you to rapidly identify which cell signaling pathways contribute to the function of your favorite genes or chemical compounds. [More Info]     SA Biosciences GEArray® Pathway-Specific DNA Microarray   SuperArray GEArray® DNA microarray systems use advanced technology to profile the expression of multiple genes on a single focused microarray. Each GEArray® is thoughtfully designed and reviewed by field experts to reflect the most current understanding of gene families. Only the most relevant genes are chosen for each application-specific microarray. The rich biological information provided by each GEArray® system improves research productivity, saving you time and money. [More Info]     Ziva - Ultrasensitive BrdU CellProliferation Assay   Ziva, developed by Jaden Bioscience, is an in vitro cell proliferation assay that can be performed in less than one hour and can detect 1-4 proliferating cells among 100,000 quiescent cells. Ziva assay is 200x more sensitive than conventional BrdU assay and offer broader dynamic range. [More Info]           #Notice to the Purchaser of EVROGEN Novel Fluorescent Proteins (Materials)   Not for Profit Entities: for non-commercial research use. With purchase of the Materials, non profit entities are granted worldwide, non-exclusive, royalty-free, limited license to use the Materials for non commercial life science research only. Such license specifically exclude the right to sell or otherwise transfer the Materials, its components or derivatives to third parties. For any other use of the Materials please contact EVROGEN at license@evrogen.com.   For Profit Entities: for non-commercial or commercial applications under license only. For license information please contact EVROGEN at license@evrogen.com.